Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR013090
| Cat. No. | CDFR013090 |
| Description | NativeORF clone of Rattus norvegicus calcium modulating ligand (Camlg) as transfection-ready DNA NM_053334.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Camlg |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | CAMLG |
| Background | The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008] |
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