Rat CDH16 ORF clone(NM_001012055.1)

Name: Rat CDH16 ORF clone(NM_001012055.1)
SKU: CDCL183482
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL183482

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Product Information

Gene Information

Cat. No.	CDCL183482
Description	ORF Clone of Rattus norvegicus cadherin 16 DNA.
Product Type	ORF clone
Gene Abbr	CDH16
Species	Rat
ORF Size	2493bp
Vector	pGEM-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

CDH16

Background

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]

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