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Rat C8B ORF clone(NM_001191759.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCG012403

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Product Information

Gene Information

Cat. No. CDCG012403
Product Type ORF clone
Gene Abbr C8B
Species Rat
Host Cell Bacterial
Source Bacteria
ORF Size 2395bp
Size 1ug
Format Clear Liquid
Vector pORF
Buffer 10mM Tris-HCI, 1mM EDTA, pH8.0
Warning pORF-rC8b ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage 1 year when stored at -20°C or lower in a non-frost free freezer.
Target Gene C8B
Background This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
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