Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDCG012403
| Cat. No. | CDCG012403 |
| Product Type | ORF clone |
| Gene Abbr | C8B |
| Species | Rat |
| Host Cell | Bacterial |
| Source | Bacteria |
| ORF Size | 2395bp |
| Size | 1ug |
| Format | Clear Liquid |
| Vector | pORF |
| Buffer | 10mM Tris-HCI, 1mM EDTA, pH8.0 |
| Warning | pORF-rC8b ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. |
| Storage | 1 year when stored at -20°C or lower in a non-frost free freezer. |
| Target Gene | C8B |
| Background | This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] |
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