Rat C4bpb cDNA Clone(NM_016995.2)

Name: Rat C4bpb cDNA Clone(NM_016995.2)
SKU: CDFR011010
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR011010

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Product Information

Gene Information

Cat. No.	CDFR011010
Description	NativeORF clone of Rattus norvegicus complement component 4 binding protein, beta (C4bpb) as transfection-ready DNA NM_016995.2
Product Type	cDAN Clone
Gene Abbr	C4bpb
Species	Rat
Vector	pCMV6Entry

Target Gene

C4BPB

Background

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]

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