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Rat Bscl2 cDNA Clone(NM_001012171.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002597

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Gene Information

Cat. No. CDFR002597
Description NativeORF clone of Rattus norvegicus Bernardinelli-Seip congenital lipodystrophy 2 homolog (human) (Bscl2) as transfection-ready DNA NM_001012171.1
Product Type cDAN Clone
Gene Abbr Bscl2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene BSCL2
Background This gene encodes the multi-pass transmembrane protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).[provided by RefSeq, Jul 2024]
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