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Rat Bre ORF Clone(NM_199270.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR382291

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Product Information

Gene Information

Cat. No. CDCR382291
Product Type ORF Clone
Gene Abbr Bre
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1152 bp
Vector pCMV6-Entry
Target Gene BRE
Background This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016]
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