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Rat Bpgm ORF Clone(NM_199382.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR382305

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Gene Information

Cat. No. CDCR382305
Product Type ORF Clone
Gene Abbr Bpgm
Species Rat
Tag C-terminal Myc-DDK
ORF Size 777 bp
Vector pCMV6-Entry
Target Gene BPGM
Background 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
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