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Rat Bmx cDNA Clone(NM_001109016.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007644

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Gene Information

Cat. No. CDFR007644
Description NativeORF clone of Rattus norvegicus BMX non-receptor tyrosine kinase (Bmx) as transfection-ready DNA NM_001109016.1
Product Type cDAN Clone
Gene Abbr Bmx
Species Rat
Vector pCMV6Entry
Target Gene BMX
Background This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
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