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Rat Bglap cDNA Clone(NM_013414.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011000

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Gene Information

Cat. No. CDFR011000
Description NativeORF clone of Rattus norvegicus bone gamma-carboxyglutamate (gla) protein (Bglap) as transfection-ready DNA NM_013414.1
Product Type cDAN Clone
Gene Abbr Bglap
Species Rat
Vector pCMV6Entry
Target Gene BGLAP
Background This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
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