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Rat Bex2 cDNA Clone(NM_001077435.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004978

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Gene Information

Cat. No. CDFR004978
Description NativeORF clone of Rattus norvegicus brain expressed X-linked 2 (Bex2) as transfection-ready DNA NM_001077435.1
Product Type cDAN Clone
Gene Abbr Bex2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene BEX2
Background This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
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