Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR008093
| Cat. No. | CDFR008093 |
| Description | NativeORF clone of Rattus norvegicus BCL2-like 12 (proline rich) (Bcl2l12) as transfection-ready DNA NM_001108480.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Bcl2l12 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | BCL2L12 |
| Background | This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
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