Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR010584
| Cat. No. | CDFR010584 |
| Description | NativeORF clone of Rattus norvegicus branched chain ketoacid dehydrogenase E1, alpha polypeptide (Bckdha) as transfection-ready DNA NM_012782.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Bckdha |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | BCKDHA |
| Background | The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). This gene encodes the alpha subunit of the decarboxylase (E1) component. Mutations in this gene result in maple syrup urine disease, type IA. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
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