Rat Bcar1 cDNA Clone(NM_012931.1)

Name: Rat Bcar1 cDNA Clone(NM_012931.1)
SKU: CDFR010629
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR010629

Inquire for Price

Product Information

Gene Information

Cat. No.	CDFR010629
Description	NativeORF clone of Rattus norvegicus breast cancer anti-estrogen resistance 1 (Bcar1) as transfection-ready DNA NM_012931.1
Product Type	cDAN Clone
Gene Abbr	Bcar1
Species	Rat
Vector	pCMV6Entry

Target Gene

BCAR1

Background

The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. [provided by RefSeq, Sep 2017]

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *