Rat B4galt3 cDNA Clone(NM_001009539.1)

Name: Rat B4galt3 cDNA Clone(NM_001009539.1)
SKU: CDFR002194
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR002194

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Product Information

Gene Information

Cat. No.	CDFR002194
Description	NativeORF clone of Rattus norvegicus UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3 (B4galt3) as transfection-ready DNA NM_001009539.1
Product Type	cDAN Clone
Gene Abbr	B4galt3
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

B4GALT3

Background

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]

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