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Rat Atxn3 cDNA Clone(NM_021702.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011749

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Gene Information

Cat. No. CDFR011749
Description NativeORF clone of Rattus norvegicus ataxin 3 (Atxn3) as transfection-ready DNA NM_021702.1
Product Type cDAN Clone
Gene Abbr Atxn3
Species Rat
Vector pCMV6Entry
Target Gene ATXN3
Background Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016]
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