Rat Atp6v1c1 cDNA Clone(NM_001011992.1)

Name: Rat Atp6v1c1 cDNA Clone(NM_001011992.1)
SKU: CDFR002421
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR002421

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Product Information

Gene Information

Cat. No.	CDFR002421
Description	NativeORF clone of Rattus norvegicus ATPase, H+ transporting, lysosomal V1 subunit C1 (Atp6v1c1) as transfection-ready DNA NM_001011992.1
Product Type	cDAN Clone
Gene Abbr	Atp6v1c1
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

ATP6V1C1

Background

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. [provided by RefSeq, Jul 2008]

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