Rat Atp1b2 ORF Clone(NM_012507.3)

Name: Rat Atp1b2 ORF Clone(NM_012507.3)
SKU: CDCR377416
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR377416

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Product Information

Gene Information

Cat. No.	CDCR377416
Product Type	ORF Clone
Gene Abbr	Atp1b2
Species	Rat
Tag	C-terminal Myc-DDK
ORF Size	873 bp
Vector	pCMV6-Entry

Target Gene

ATP1B2

Background

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

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