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Rat Atp1a1 cDNA Clone(NM_012504.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010182

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Gene Information

Cat. No. CDFR010182
Description NativeORF clone of Rattus norvegicus ATPase, Na+/K+ transporting, alpha 1 polypeptide (Atp1a1) as transfection-ready DNA NM_012504.1
Product Type cDAN Clone
Gene Abbr Atp1a1
Species Rat
Vector pCMV6Entry
Target Gene ATP1A1
Background The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
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