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Rat Atic cDNA Clone(NM_031014.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012490

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Gene Information

Cat. No. CDFR012490
Description NativeORF clone of Rattus norvegicus 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (Atic) as transfection-ready DNA NM_031014.2
Product Type cDAN Clone
Gene Abbr Atic
Species Rat
Vector pCMV6Entry
Target Gene ATIC
Background This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]
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