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Rat Atg5 ORF Clone(NM_001014250.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR370379

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Product Information

Gene Information

Cat. No. CDCR370379
Product Type ORF Clone
Gene Abbr Atg5
Species Rat
Tag C-terminal Myc-DDK
ORF Size 654 bp
Vector pCMV6-Entry
Target Gene ATG5
Background The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
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