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Rat Atf6b cDNA Clone(NM_001002809.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001215

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Gene Information

Cat. No. CDFR001215
Description NativeORF clone of Rattus norvegicus activating transcription factor 6 beta (Atf6b) as transfection-ready DNA NM_001002809.3
Product Type cDAN Clone
Gene Abbr Atf6b
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ATF6B
Background The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
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