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Rat Aspn cDNA Clone(NM_001014008.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003085

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Gene Information

Cat. No. CDFR003085
Description NativeORF clone of Rattus norvegicus asporin (Aspn) as transfection-ready DNA NM_001014008.1
Product Type cDAN Clone
Gene Abbr Aspn
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ASPN
Background This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants.[provided by RefSeq, Jul 2014]
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