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Rat Asic2 cDNA Clone(NM_001034014.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004332

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Gene Information

Cat. No. CDFR004332
Description NativeORF clone of Rattus norvegicus amiloride-sensitive cation channel 1, neuronal (Accn1), transcript variant 2 as transfection-ready DNA NM_001034014.1
Product Type cDAN Clone
Gene Abbr Asic2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ASIC2
Background This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012]
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