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Rat Ascc1 cDNA Clone(NM_001007632.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001642

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Gene Information

Cat. No. CDFR001642
Description NativeORF clone of Rattus norvegicus activating signal cointegrator 1 complex subunit 1 (Ascc1) as transfection-ready DNA NM_001007632.2
Product Type cDAN Clone
Gene Abbr Ascc1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ASCC1
Background This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
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