Rat Arrb2 cDNA Clone(NM_012911.1)

Name: Rat Arrb2 cDNA Clone(NM_012911.1)
SKU: CDFR010621
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR010621

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Product Information

Gene Information

Cat. No.	CDFR010621
Description	NativeORF clone of Rattus norvegicus arrestin, beta 2 (Arrb2) as transfection-ready DNA NM_012911.1
Product Type	cDAN Clone
Gene Abbr	Arrb2
Species	Rat
Vector	pCMV6Entry

Target Gene

ARRB2

Background

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

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