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Rat Arhgef6 cDNA Clone(NM_001005565.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001307

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Gene Information

Cat. No. CDFR001307
Description NativeORF clone of Rattus norvegicus Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (Arhgef6) as transfection-ready DNA NM_001005565.1
Product Type cDAN Clone
Gene Abbr Arhgef6
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ARHGEF6
Background Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability. [provided by RefSeq, Jul 2008]
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