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Rat Arhgdib ORF Clone(NM_001009600.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR369212

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Product Information

Gene Information

Cat. No. CDCR369212
Product Type ORF Clone
Gene Abbr Arhgdib
Species Rat
Tag C-terminal Myc-DDK
ORF Size 603 bp
Vector pCMV6-Entry
Target Gene ARHGDIB
Background Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010]
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