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Rat Arhgdia cDNA Clone(NM_001007005.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001582

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Gene Information

Cat. No. CDFR001582
Description NativeORF clone of Rattus norvegicus Rho GDP dissociation inhibitor (GDI) alpha (Arhgdia) as transfection-ready DNA NM_001007005.1
Product Type cDAN Clone
Gene Abbr Arhgdia
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ARHGDIA
Background This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
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