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Rat Arg2 cDNA Clone(NM_019168.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011466

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Gene Information

Cat. No. CDFR011466
Description NativeORF clone of Rattus norvegicus arginase type II (Arg2) as transfection-ready DNA NM_019168.1
Product Type cDAN Clone
Gene Abbr Arg2
Species Rat
Vector pCMV6Entry
Target Gene ARG2
Background Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008]
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