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Rat Arfgap3 ORF Clone(NM_001044273.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR371814

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Gene Information

Cat. No. CDCR371814
Product Type ORF Clone
Gene Abbr Arfgap3
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1578 bp
Vector pCMV6-Entry
Target Gene ARFGAP3
Background The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008]
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