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Rat Aplp1 cDNA Clone(NM_001100802.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005364

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Gene Information

Cat. No. CDFR005364
Description NativeORF clone of Rattus norvegicus amyloid beta (A4) precursor-like protein 1 (Aplp1) as transfection-ready DNA NM_001100802.1
Product Type cDAN Clone
Gene Abbr Aplp1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene APLP1
Background This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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