Rat Apeh cDNA Clone(NM_012500.1)

Name: Rat Apeh cDNA Clone(NM_012500.1)
SKU: CDFR010178
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR010178

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Product Information

Gene Information

Cat. No.	CDFR010178
Description	NativeORF clone of Rattus norvegicus N-acylaminoacyl-peptide hydrolase (Apeh) as transfection-ready DNA NM_012500.1
Product Type	cDAN Clone
Gene Abbr	Apeh
Species	Rat
Vector	pCMV6Entry

Target Gene

APEH

Background

This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. [provided by RefSeq, Jul 2008]

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