Pages
Products

Rat Apbb1 cDNA Clone(NM_080478.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013469

Inquire for Price

Product Information

Gene Information

Cat. No. CDFR013469
Description NativeORF clone of Rattus norvegicus amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (Apbb1) as transfection-ready DNA NM_080478.1
Product Type cDAN Clone
Gene Abbr Apbb1
Species Rat
Vector pCMV6Entry
Target Gene APBB1
Background The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction