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Rat Ap4s1 cDNA Clone(NM_001130999.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR009388

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Gene Information

Cat. No. CDFR009388
Description NativeORF clone of Rattus norvegicus adaptor-related protein complex AP-4, sigma 1 (Ap4s1) as transfection-ready DNA NM_001130999.1
Product Type cDAN Clone
Gene Abbr Ap4s1
Species Rat
Vector pCMV6Entry
Target Gene AP4S1
Background This gene encodes a member of the adaptor complexes small subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is the small subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Mutations in this gene are associated with spastic quadriplegic cerebral palsy-6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Dec 2011]
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