Rat Ap3m1 cDNA Clone(NM_133593.2)

Name: Rat Ap3m1 cDNA Clone(NM_133593.2)
SKU: CDFR014106
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR014106

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Product Information

Gene Information

Cat. No.	CDFR014106
Description	NativeORF clone of Rattus norvegicus adaptor-related protein complex 3, mu 1 subunit (Ap3m1) as transfection-ready DNA NM_133593.2
Product Type	cDAN Clone
Gene Abbr	Ap3m1
Species	Rat
Vector	pCMV6Entry

Target Gene

AP3M1

Background

The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]

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