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Rat Angptl4 cDNA Clone(NM_199115.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR015038

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Gene Information

Cat. No. CDFR015038
Description NativeORF clone of Rattus norvegicus angiopoietin-like 4 (Angptl4) as transfection-ready DNA NM_199115.2
Product Type cDAN Clone
Gene Abbr Angptl4
Species Rat
Target Gene ANGPTL4
Background This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013]
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