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Rat Anapc2 cDNA Clone(NM_001100532.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005087

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Gene Information

Cat. No. CDFR005087
Description NativeORF clone of Rattus norvegicus anaphase promoting complex subunit 2 (Anapc2) as transfection-ready DNA NM_001100532.1
Product Type cDAN Clone
Gene Abbr Anapc2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ANAPC2
Background A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008]
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