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Rat Aldoa cDNA Clone(NM_012495.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010173

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Gene Information

Cat. No. CDFR010173
Description NativeORF clone of Rattus norvegicus aldolase A, fructose-bisphosphate (Aldoa) as transfection-ready DNA NM_012495.2
Product Type cDAN Clone
Gene Abbr Aldoa
Species Rat
Vector pCMV6Entry
Target Gene ALDOA
Background This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]
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