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Rat Akr7a2 cDNA Clone(NM_134407.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014200

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Gene Information

Cat. No. CDFR014200
Description NativeORF clone of Rattus norvegicus aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (Akr7a2) as transfection-ready DNA NM_134407.1
Product Type cDAN Clone
Gene Abbr Akr7a2
Species Rat
Vector pCMV6Entry
Target Gene AKR7A2
Background The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
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