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Rat Akr1c2 cDNA Clone(NM_001013057.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002786

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Gene Information

Cat. No. CDFR002786
Description NativeORF clone of Rattus norvegicus aldo-keto reductase family 1, member C21 (Akr1c21) as transfection-ready DNA NM_001013057.1
Product Type cDAN Clone
Gene Abbr Akr1c2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene AKR1C2
Background This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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