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Rat Akr1b1 cDNA Clone(NM_012498.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010176

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Gene Information

Cat. No. CDFR010176
Description NativeORF clone of Rattus norvegicus aldo-keto reductase family 1, member B1 (aldose reductase) (Akr1b1) as transfection-ready DNA NM_012498.1
Product Type cDAN Clone
Gene Abbr Akr1b1
Species Rat
Vector pCMV6Entry
Target Gene AKR1B1
Background This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
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