Rat Akap12 cDNA Clone(NM_057103.2)

Name: Rat Akap12 cDNA Clone(NM_057103.2)
SKU: CDFR013720
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013720

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Product Information

Gene Information

Cat. No.	CDFR013720
Description	NativeORF clone of Rattus norvegicus A kinase (PRKA) anchor protein 12 (Akap12), transcript variant 1 as transfection-ready DNA NM_057103.2
Product Type	cDAN Clone
Gene Abbr	Akap12
Species	Rat
Vector	pCMV6Entry

Target Gene

AKAP12

Background

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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