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Rat Agr3 cDNA Clone(NM_001106724.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006277

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Gene Information

Cat. No. CDFR006277
Description NativeORF clone of Rattus norvegicus anterior gradient homolog 3 (Xenopus laevis) (Agr3) as transfection-ready DNA NM_001106724.1
Product Type cDAN Clone
Gene Abbr Agr3
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene AGR3
Background This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016]
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