Pages
Products

Rat Adsl ORF Clone(NM_001130503.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR376739

Inquire for Price

Product Information

Gene Information

Cat. No. CDCR376739
Product Type ORF Clone
Gene Abbr Adsl
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1455 bp
Vector pCMV6-Entry
Target Gene ADSL
Background The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction