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Rat Acr cDNA Clone(NM_012490.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010168

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Gene Information

Cat. No. CDFR010168
Description NativeORF clone of Rattus norvegicus acrosin (Acr) as transfection-ready DNA NM_012490.2
Product Type cDAN Clone
Gene Abbr Acr
Species Rat
Vector pCMV6Entry
Target Gene ACR
Background Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq, Jul 2008]
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