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Rat Acly cDNA Clone(NM_001111095.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR009279

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Gene Information

Cat. No. CDFR009279
Description NativeORF clone of Rattus norvegicus ATP citrate lyase (Acly), transcript variant 2 as transfection-ready DNA NM_001111095.1
Product Type cDAN Clone
Gene Abbr Acly
Species Rat
Vector pCMV6Entry
Target Gene ACLY
Background ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]
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