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Rat Abl2 cDNA Clone(NM_001107186.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006911

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Gene Information

Cat. No. CDFR006911
Description NativeORF clone of Rattus norvegicus v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) (Abl2) as transfection-ready DNA NM_001107186.1
Product Type cDAN Clone
Gene Abbr Abl2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ABL2
Background This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
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