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Rat Abcd4 cDNA Clone(NM_001013100.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002828

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Gene Information

Cat. No. CDFR002828
Description NativeORF clone of Rattus norvegicus ATP-binding cassette, sub-family D (ALD), member 4 (Abcd4) as transfection-ready DNA NM_001013100.3
Product Type cDAN Clone
Gene Abbr Abcd4
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ABCD4
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. [provided by RefSeq, Jul 2017]
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