Panoply™ Human ZAK Knockdown Stable Cell Line

Name: Panoply™ Human ZAK Knockdown Stable Cell Line
SKU: CSC-DC017653
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC017653

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC017653
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ZAK
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ZAK sterile alpha motif and leucine zipper containing kinase AZK [ Homo sapiens ]
Gene Symbol	ZAK
Synonyms	pk; AZK; MLT; MRK; MLK7; MLTK; mlklak
Gene Description	sterile alpha motif and leucine zipper containing kinase AZK
GeneID	65964
Uni ProtID	D4Q8H0
mRNA Refseq	NM_133646.2
Protein Refseq	NP_598407.1
Chromosome Location	2q24.2
Function	ATP binding; MAP kinase kinase kinase activity; magnesium ion binding; protein binding; protein serine/threonine kinase activity;
Pathway	MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Signaling mediated by p38-gamma and p38-delta, organism-specific biosystem; Tight junction, organism-specific biosystem; Tight junction, conserved biosystem;
MIM	609479

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