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Panoply™ Human VAV1 Knockdown Stable Cell Line

Cat.No.
CSC-DC017243
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
VAV1
Synonyms
VAV1; vav 1 guanine nucleotide exchange factor; VAV, vav 1 oncogene; proto-oncogene vav; vav 1 oncogene; VAV;
Gene ID
UniProt ID
P15498
mRNA Refseq
BC013361
Chromosome Location
19p13.2
Function
Rac guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; metal ion binding; protein binding; sequence-specific DNA binding transcription factor activity;
Pathway
Adaptive Immune System, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent Vav1 pathway, organism-specific biosystem;
MIM

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